Randy D Blakely Selected Research

choline transporter

1/2022	Disrupted Choline Clearance and Sustained Acetylcholine Release In Vivo by a Common Choline Transporter Coding Variant Associated with Poor Attentional Control in Humans.
8/2019	Repetitive mild concussion in subjects with a vulnerable cholinergic system: Lasting cholinergic-attentional impairments in CHT+/- mice.
11/2017	Choline transporter mutations in severe congenital myasthenic syndrome disrupt transporter localization.
12/2013	Monitoring cholinergic activity during attentional performance in mice heterozygous for the choline transporter: a model of cholinergic capacity limits.
2/2013	The presynaptic choline transporter imposes limits on sustained cortical acetylcholine release and attention.
9/2010	Tachycardia, reduced vagal capacity, and age-dependent ventricular dysfunction arising from diminished expression of the presynaptic choline transporter.
12/2009	Choline transporter gene variation is associated with attention-deficit hyperactivity disorder.

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Randy D Blakely Research Topics

Disease

17	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 01/2019 - 11/2005
14	Autistic Disorder (Autism) 01/2022 - 08/2005
12	Autism Spectrum Disorder 04/2021 - 06/2009
8	Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive) 04/2021 - 08/2005
7	Mood Disorders (Mood Disorder) 01/2021 - 09/2002
7	Paralysis (Palsy) 01/2019 - 06/2006
6	Mental Disorders (Mental Disorder) 01/2022 - 06/2004
5	Parkinson Disease (Parkinson's Disease) 01/2022 - 07/2003
5	Brain Diseases (Brain Disorder) 01/2020 - 07/2007
4	Bipolar Disorder (Manic Depressive Psychosis) 01/2022 - 01/2018
4	Major Depressive Disorder (Major Depressive Disorders) 01/2020 - 11/2007
4	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2018 - 06/2006
3	Cognitive Dysfunction 01/2022 - 02/2013
3	Schizophrenia (Dementia Praecox) 01/2018 - 12/2009
2	Inflammation (Inflammations) 01/2021 - 01/2017
2	Cocaine-Related Disorders (Cocaine Addiction) 01/2019 - 08/2017
2	Hypersensitivity (Allergy) 10/2018 - 04/2012
2	Anxiety Disorders (Anxiety Disorder) 01/2013 - 11/2011
2	Alzheimer Disease (Alzheimer's Disease) 12/2009 - 12/2003
2	Leukemia 07/2007 - 06/2004
2	Cardiovascular Diseases (Cardiovascular Disease) 06/2006 - 08/2005
2	Burkitt Lymphoma (Burkitt's Lymphoma) 07/2005 - 04/2002
1	Albuminuria 01/2022
1	Movement Disorders (Movement Disorder) 01/2021
1	Wounds and Injuries (Trauma) 08/2019
1	Brain Concussion (Cerebral Concussion) 08/2019
1	Traumatic Brain Injuries (Traumatic Brain Injury) 08/2019
1	Body Weight (Weight, Body) 01/2018
1	Nerve Degeneration 01/2018
1	Congenital Myasthenic Syndromes (Myasthenia Gravis, Congenital) 11/2017
1	Neuroinflammatory Diseases 09/2017
1	Head and Neck Neoplasms (Head and Neck Cancer) 03/2012
1	Eczema 11/2011
1	Tachycardia (Tachyarrhythmias) 09/2010
1	Ventricular Dysfunction 09/2010
1	Hypertrophy 01/2010
1	Heart Failure 01/2010
1	Left Ventricular Dysfunction 01/2010
1	Developmental Disabilities (Developmental Disability) 07/2009
1	Alcoholism (Alcohol Abuse) 02/2009
1	Amphetamine-Related Disorders (Addiction, Amphetamine) 03/2008
1	Constipation 01/2007
1	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 01/2007
1	Neuroblastoma 08/2005
1	Neoplasms (Cancer) 07/2005

Drug/Important Bio-Agent (IBA)

28	Serotonin (5 Hydroxytryptamine)IBA 04/2021 - 04/2002
15	Dopamine (Intropin)FDA LinkGeneric 01/2022 - 04/2010
9	Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)IBA 01/2017 - 07/2005
8	Cholinergic Agents (Cholinergics)IBA 01/2022 - 02/2004
8	Biomarkers (Surrogate Marker)IBA 04/2021 - 06/2009
7	choline transporterIBA 01/2022 - 12/2009
7	Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA 01/2019 - 11/2005
6	Amphetamine (Amfetamine)FDA LinkGeneric 04/2015 - 07/2005
5	Proteins (Proteins, Gene)FDA Link 01/2021 - 08/2005
4	Cocaine (Cocaine HCl)IBA 01/2019 - 03/2008
4	Norepinephrine (Noradrenaline)FDA LinkGeneric 10/2011 - 08/2005
3	Pharmaceutical PreparationsIBA 01/2019 - 01/2007
3	Antidepressive Agents (Antidepressants)IBA 03/2011 - 07/2005
3	Norepinephrine Plasma Membrane Transport Proteins (Norepinephrine Transporter)IBA 01/2008 - 06/2003
2	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 01/2021 - 04/2002
2	Transcription Factors (Transcription Factor)IBA 01/2019 - 12/2006
2	p38 Mitogen-Activated Protein KinasesIBA 10/2018 - 07/2007
2	AutoreceptorsIBA 01/2017 - 04/2010
2	Methylphenidate (Ritalin)FDA LinkGeneric 07/2014 - 07/2008
2	Serotonin ReceptorsIBA 10/2013 - 04/2012
2	Choline (Choline Chloride)IBA 02/2013 - 06/2006
2	Monoamine Oxidase (MAO)IBA 01/2010 - 07/2009
2	Purinergic P1 Receptors (Adenosine Receptor)IBA 07/2007 - 06/2004
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2022
1	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2022
1	NexusIBA 01/2021
1	Histamine Receptors (Histamine Receptor)IBA 01/2021
1	Histamine (Histamine Dihydrochloride)FDA Link 01/2021
1	GTP-Binding Protein alpha SubunitsIBA 01/2021
1	Escitalopram FDA Link 01/2021
1	gamma-Aminobutyric Acid (GABA)IBA 01/2019
1	AzaperoneIBA 01/2019
1	Aldicarb (Temik)IBA 01/2019
1	Aminobutyrates (Aminobutyric Acid)IBA 01/2019
1	Glucose (Dextrose)FDA LinkGeneric 01/2018
1	Carisoprodol (Soma)FDA LinkGeneric 01/2018
1	Cystine (L-Cystine)IBA 01/2018
1	Ceftriaxone (Ceftriaxon)FDA LinkGeneric 10/2017
1	Neurotransmitter Agents (Neurotransmitter)IBA 01/2017
1	nisoxetineIBA 01/2016
1	Adenosine A3 ReceptorIBA 08/2013
1	Biological ProductsIBA 08/2013
1	AntigensIBA 11/2011
1	CatecholaminesIBA 01/2010
1	Adrenergic Receptors (Adrenergic Receptor)IBA 01/2010
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2010
1	Cholinergic AgonistsIBA 12/2009
1	rimcazoleIBA 03/2008
1	Benztropine (Benzatropine)FDA LinkGeneric 03/2008
1	Desvenlafaxine Succinate FDA Link 11/2007
1	tegaserod (Zelnorm)FDA Link 01/2007
1	CytokinesIBA 10/2006
1	DNA (Deoxyribonucleic Acid)IBA 11/2005

Therapy/Procedure

6	Therapeutics 04/2012 - 09/2002
2	Quantum Dots (Quantum Dot) 01/2019 - 04/2015